For Okinawa, under 30 samples had been shared covering the recent wave there, naking it very difficult to draw any conclusions. Suddenly a further 400+ samples have been shared in recent days. This massive dump has revealed that the EG.5.* "Eris" variant (11%) has not been signifcant in Okinawa.
Instead, it seems the wave in Okinawa was driven by XBB.1.16.* "Arcturus" (38%).
The variant hunters are pouring over the new data, and have identified a couple of suspect sub-lineages - as-yet undesignated:
- XBB.1.16 with a Spike E748Q mutation (18%). This combination is globally unique to Okinawa from late-June, and shows the cleanest growth curve. However it has not been detected in the most recent week or so of sample data from Okinawa, which is surprising. Perhaps ("hopefully"), it might cause more severe disease, but have a transmission disadvantage? If so, humanity can perhaps breathe a sigh of releif, and get back to rolling the dice on other mutation combinations.
- XBB.1.16 with an E:P71S mutation (10%). This combination has been fairly common in several Japanese prefectures (as well as Okinawa), so this one seems a little less likely.
バリアントハンターたちは新しいデータに目を通し、まだ指定されていない疑わしい亜系をいくつか特定した:
- XBB.1.16とスパイクE748Q変異(18%)。この組み合わせは、6月下旬から沖縄で発生した世界的にユニークなもので、最もきれいな成長曲線を示している。しかし、最近1週間ほどの沖縄のサンプルデータでは検出されていない。ひょっとすると(「うまくいけば」)、より重篤な病気を引き起こすかもしれないが、感染には不利なのだろうか?もしそうなら、人類はほっと一息ついて、他の変異の組み合わせのサイコロを振ることに戻れるかもしれない。
- XBB.1.16とE:P71S変異(10%)。この組み合わせは(沖縄だけでなく)日本のいくつかの県でかなりよく見られるので、この可能性は少し低いと思われる。
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